If you are exploring ways to support your skin’s appearance and quality, Rejuran is one treatment worth understanding. This injectable skin treatment, originally developed in South Korea, uses polynucleotides (PNs) — DNA fragments derived from salmon — to support the skin’s own regenerative processes.
It is worth noting that Rejuran is not a volume-adding injectable treatment. Rather than adding volume to a specific area, Rejuran works gradually by supporting the skin’s natural ability to repair and renew itself. Results develop over time and vary between individuals.
What is Rejuran Skin Treatment?
Rejuran is a skin rejuvenation treatment that uses polynucleotides (PNs) derived from salmon DNA. These naturally occurring molecules are intended to support the skin’s repair processes and collagen production.
Rejuran is generally used to support skin texture, hydration and elasticity, and to soften the appearance of fine lines and wrinkles. Rather than adding facial volume, it works by supporting the skin’s own repair and renewal processes. It does this by activating the skin’s fibroblast cells, which produce collagen and elastin — proteins that contribute to skin strength and resilience.
While Rejuran may help support skin quality, it should not be viewed as a one-off fix for all skin concerns. It works gradually, results vary from person to person, and it is not suitable for everyone.
How Does Rejuran Work?
Rejuran is administered as a series of micro-injections that introduce polynucleotides (PNs) into the skin. Once injected, the PNs are intended to activate fibroblast cells, which are involved in collagen and elastin production, supporting the skin’s own repair processes. The gel-like formulation can also act as a temporary scaffold for the skin’s natural healing.
Over time, this may contribute to improvements in skin elasticity, hydration and texture. It is important to note that any changes are gradual, with visible improvements typically developing over several weeks rather than immediately.
Rejuran is not an overnight treatment. Improvements build gradually, more than one session is usually needed, and your healthcare professional can advise you on a suitable approach after assessing your skin.
Potential Benefits of Rejuran
The following are potential benefits. They are not guaranteed, and how much any individual notices — if anything — varies from person to person.
1. Collagen Support and Skin Regeneration
Rejuran may help support collagen production, which can contribute to skin strength and firmness. Collagen is an important protein for maintaining the skin’s structure and elasticity.
2. Skin Hydration and Elasticity
While it is not a dedicated hydration treatment, Rejuran may support the skin’s ability to retain moisture by supporting its natural repair processes. This can contribute to hydration and elasticity, which help keep skin resilient.
3. Appearance of Fine Lines, Wrinkles and Scarring
By supporting collagen and elastin production, Rejuran may help soften the appearance of fine lines and wrinkles. Over time, gradual changes in skin structure and elasticity may contribute to the overall appearance of the skin. As above, results vary and more than one session is often required.
4. Skin Tone and Texture
Rejuran may help support skin quality by supporting the skin’s natural repair processes in response to factors such as sun exposure, acne scars and other concerns. It may contribute to more even skin tone and texture and support the skin barrier’s resilience to environmental stressors.
Who is Rejuran For?
Rejuran may be considered by people experiencing early signs of ageing, such as fine lines, wrinkles or loss of skin firmness. It may also be an option for those with dull or dehydrated skin, uneven texture, or certain types of scarring, including some acne scarring.
As with any cosmetic procedure, it is important to consult a qualified healthcare professional who can assess your skin and determine whether Rejuran is appropriate for you. Not everyone is a suitable candidate — for example, people with certain skin conditions or active acne may not be suitable.
What to Expect During a Rejuran Treatment
A Rejuran treatment typically involves the following steps:
- Consultation: A thorough consultation with a qualified healthcare professional is essential to determine whether Rejuran is suitable for your concerns. Your practitioner will discuss the procedure, the potential risks, the recovery and what a realistic outcome might be.
- Treatment: Rejuran is administered through micro-injections. A topical numbing cream is usually applied beforehand to help with comfort, though comfort varies between individuals. The procedure typically takes about 30 to 60 minutes.
- Aftercare: After treatment, some people experience mild swelling, bruising, redness or tenderness at the injection sites, and small temporary bumps can occur. These effects usually settle within about 5–7 days. Less commonly, injection treatments can carry a risk of infection or other reactions. Follow the aftercare instructions provided by your practitioner.
- Results: Rejuran works gradually, with changes typically developing over several weeks. A course of around 3–4 treatments, spaced roughly 2–4 weeks apart, is often suggested, though this is individualised and results are not guaranteed.
Having any injectable treatment is a considered decision that carries risks as well as potential benefits. These are discussed with you during your consultation.
Rejuran and Gradual Skin Rejuvenation
Rejuran is used in aesthetic care as an option for people who prefer a gradual approach that works with the skin’s own regenerative processes rather than adding volume. A natural-looking change is the clinical aim, but outcomes develop over time and vary between individuals.
Rejuran is also intended to help support the skin barrier, which may contribute to the skin’s resilience against everyday environmental factors and the changes associated with ageing, a natural process.
Learn More About Rejuran at MedAesthetics
If you are considering Rejuran to help address concerns such as fine lines, wrinkles or uneven texture, it is important to consult a qualified healthcare professional. At MedAesthetics, we can assess your skin’s needs and, if treatment is suitable, provide a personalised plan with a clear explanation of the benefits, the limitations and the risks. Rejuran offers gradual changes that work with the skin’s regenerative processes; results develop over time and vary from person to person.
Contact us to arrange a consultation.
Please note that this information is provided for educational purposes only and is not a substitute for professional medical advice. Individual results may vary, and consultation with a qualified healthcare provider is recommended before undertaking any aesthetic treatment.
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